A novel strategy using lipid nanoparticles to reprogram liver immunity shows promise in generating antitumor responses ...

As spring nears and the weather warms, the Georgia Department of Natural Resources is reminding Georgians that clean bird feeders mean less health risks for birds.

Specifically, CD62L-CD86 + myeloid dendritic cells and CD86 + myeloid dendritic cells demonstrated protective effects, whereas CD14 + CD16 + monocytes were identified as risk factors. Furthermore, the ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Significant advancements have recently been achieved in the ...

School of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China School of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China Shenyang Key ...

These cytokines also serve to further activate T regs. Activated T regs upregulate CTLA-4, which selectively binds to CD80 and CD86 on APCs blocking interaction between CD80/86 and CD28 on ...

Despite the mechanisms of central and peripheral tolerance, the mature B cell compartment contains cells reactive for self-antigen. How these cells are poised not to respond and the mechanisms that ...

Single-cell measurements of cellular characteristics have been instrumental in understanding the heterogeneous pathways that drive differentiation, cellular responses to signals, and human disease.

Macrophages can present antigens to and activate T lymphocytes. Two important co-stimulatory molecules are the cell-surface proteins B7.1 (CD80) and B7.2 (CD86), which are induced on macrophages and ...