American Association of Individual Investors2d
Why RAPT Therapeutics, Inc.’s (RAPT) Stock Is Up 16.79%
RAPT Therapeutics, Inc.’s RAPT share price has surged by 16.79%, which has investors questioning if this is right time to ...
The EMBO Journal1mon
Lanatoside C activates the E3 ligase STUB1 to inhibit FOXP3 transcriptional activity and promote antitumor immunity
This month's cover highlights the article Boosting human immunology: Harnessing the potential of immune organoids by Dirk Baumjohann and Maximilian Moll. The review article explores recent advances in ...
Frontiers1y
Radiofrequency ablation plays double role in immunosuppression and activation of PBMCs in recurrent hepatocellular carcinoma
Doublets were removed according to the Even Length. Furthermore, CD45 gate were used to isolate all the blood leukocyte, then a clustering panel including CD3, CD4, CD8A, CCR4, CCR5, CCR7, HLA-DR, ...
Frontiers1y
CCL17 and CCL22 chemokines are upregulated in human obesity and play a role in vascular dysfunction
The aim of this study was to investigate the role of chemokine receptor CCR4 and its ligands CCL17 and CCL22 in human morbid obesity. Results: Compared with controls, morbidly obese patients presented ...
eLife6y
RNA-binding proteins distinguish between similar sequence motifs to promote targeted deadenylation by Ccr4-Not
The Ccr4-Not complex removes mRNA poly(A) tails to regulate eukaryotic mRNA stability and translation. RNA-binding proteins contribute to specificity by interacting with both Ccr4-Not and target mRNAs ...