1 Hereditary angioedema with reduced C1 esterase inhibitor (C1-INH) function (HAE-C1-INH) is the most common, leading to excess bradykinin and increased vascular permeability. Hereditary angioedema ...

Preliminary results from the 111-subject study revealed that a 3.6mg/kg dose of trontinemab reduced amyloid levels below the 24 centiloid threshold – a commonly used cutoff point used to predict ...

The phase 3b STEP UP trial in more than 1,400 patients compared a 7.2mg weekly subcutaneous injection of semaglutide to the standard 2.6mg weekly dose sold as Wegovy or a matched placebo.