Barth syndrome is caused by a mutation in the tafazzin gene, which results in reduced cardiolipin levels, a phospholipid that plays a major role in mitochondrial function. The disease is ...

KL-1333M is under development for the treatment of mitochondrial myopathy such as MELAS syndrome (Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke), Kearns-Sayre syndrome, Pearson ...

the researchers used an advanced home-built microscope to look at single proteins on individual DNA molecules. That in itself is an impressive achievement, as Barth explains: "A single cell ...

A senior at Academy of Notre Dame, Katie Barth is a Global Citizen Scholar candidate, a Blue and Gold Key Society member, and active member of Mock Trial and Model UN clubs and started Academy of ...

Mitochondria are now known to not only generate energy but also produce essential cellular materials, adapting uniquely to stress, which sheds light on cancer survival tactics and aging processes.

Using electron microscopy, the team was able to visualize the trapped proteins at a specific moment during the reaction and uncovered new ways the proteins coordinate their actions, which helps ...

Most of us remember two things from high school biology: that mitochondria are the powerhouses of cells and that we inherit stable sets of chromosomes from our two parents. Both truisms are only ...

is under development for the treatment of primary mitochondrial diseases including mitochondrial myopathy, Senger syndrome, Barth syndrome, dry age-related macular degeneration, Duchenne muscular ...

seeks to explain the cellular defects underlying the brain phenotypes of Lowe syndrome (LS). There have been limited ... These two models are used to present three separate findings: (1) altered ...

The Samuel Roberts Noble Microscopy Laboratory, the core microscopy facility of the University of Oklahoma-Norman, offers access to instrumentation, training, and service. Our mission is to provide ...