Huntington’s disease symptoms are linked to expanding DNA repeats (CAG) that become toxic in brain cells over time The "ticking DNA clock" accelerates after 80 repeats, killing neurons within ...

The team found that although functions such as movement, thinking or behavior remained normal for a long time before the onset of symptoms in Huntington's disease, subtle changes to the brain were ...

The team found that although functions such as movement, thinking or behaviour remained normal for a long time before the onset of symptoms in Huntington's disease, subtle changes to the brain ...

The team found that although functions such as movement, thinking or behavior remained normal for a long time before the onset of symptoms in Huntington's disease, subtle changes to the brain were ...

This type of "somatic expansion" occurs in only the specific types of brain cells that later die in Huntington's disease. Only once a cell's DNA expansion reaches a threshold number of CAGs ...

Huntington's disease, a fatal hereditary brain disorder, is linked to a genetic mutation that remains harmless for decades before expanding and producing toxic proteins that kill brain cells.

Scientists have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells. The findings change the ...

Researchers have made a major breakthrough in our understanding of Huntington's disease. This genetic disorder has long been known to be caused by mutations in the huntingtin gene, which leads to the ...

CAMBRIDGE, Massachusetts ‒ For decades it's been one of the defining mysteries of Huntington's disease. Why does the terrible devastation of mind and body start earlier in some people who ...

For many people, the symptoms of Huntington's disease will not begin to show for decades. The genetic disorder is incurable but it is not uncommon for sufferers to reach middle-age before the ...

BOSTON — Scientists are unraveling the mystery of what triggers Huntington's disease, a devastating and fatal hereditary disorder that strikes in the prime of life, causing nerve cells in parts ...