Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Purified FICD and BiP protein concentrations were measured ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. m 6 A RNA modification has been linked to ...
Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, Iowa 50011, United States ...
BTM-3566 is a first-in-class, small molecule cancer therapeutic which targets mitochondrial homeostasis via the ATF4-Integrated Stress Response (ISR) pathway to treat aggressive tumors. “We are ...
Western blot was used to determine the levels of PeIF2α, eIF2α, ATF4, GADD34, CHOP, BDNF, proBDNF, and p-NR2B expression. The levels of reactive oxygen species (ROS), superoxide dismutase (SOD), and ...
GDF-15, growth differentiation factor 15; GFRAL, glial cell-derived neurotrophic factor (GDNF) family receptor alpha-like (GFRAL); ATF4, activating transcription factor 4; CHOP, C/EBP homologous ...
The melanoma-associated antigen family A (MAGEA) antigens are expressed in a wide variety of malignant tumors but not in adult somatic cells, rendering them attractive targets for cancer immunotherapy ...
Regular exercise has widespread health benefits. Fundamental to these beneficial effects is the ability of the heart to intermittently and substantially increase its performance without incurring ...