MIT neuroscientists have made a breakthrough in treating fragile X syndrome by leveraging a novel neurotransmitter signaling ...

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Brain astrocytes and microglia causes excessive removal of synapses at the early stage of stroke. Inhibition of their phagocytosis improved neurobehavioral outcomes. Long-term post-stroke cognitive ...

Pain is an example of an important sensory neuron. When you feel pain from a hot pan or a sharp pin, you are sending sensory information via sensory neurons up to the brain. The flow of electrical ...

Get Instant Summarized Text (Gist) An experimental drug, LL-341070, has been shown to accelerate myelin repair in the brain, improving vision in mice with severe myelin damage. This drug enhances ...

iAssembloids combine hiPSC-derived neurons, microglia, and astrocytes in 3D spheres. CRISPRi screening revealed genes that affect neuron survival in iAssembloids but not in 2D monoculture. One gene, ...

Rabah et al. discover an astrocyte-to-neuron hydrogen peroxide signalling cascade, which is crucial for long-term memory formation in Drosophila. This signalling is found to be inhibited by ...

The nucleus where the genes that modify neuron function are controlled is a long distance away from where neurons receive input from their synapses, which are located in distant dendrites that ...

Mark Dell'Acqua, professor of pharmacology at the University of Colorado Anschutz Medical Campus and senior author of the study The nucleus where the genes that modify neuron function are ...

Age-associated neurodegenerative diseases, including dementias, such as Alzheimer’s disease (AD) and Frontotemporal dementia (FTD), and clinically overlapping conditions such as Parkinson’s Disease ...