MSS Adenoma-carcinoma sequence 5 (Lynch syndrome) CIMP negative, MSI-H Adenoma-carcinoma sequence CIMP = CpG island methylator phenotype; MSI-H = High-frequency microsatellite instability ...
Figure 2: Contrasting effects of telomere shortening on tumor formation in Apc Min mice. Figure 5: Telomere dysfunction peaks at the adenoma-carcinoma ... intestinal rolls spanning the entire ...
Nat Clin Pract Gastroenterol Hepatol. 2006;3(5):267-274. An adaptation of the Vogelstein adenoma:carcinoma sequence. The acquisition of a mutation (or 'hit') in a stem cell within a crypt ...
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