CERo Therapeutics has announced that Colorado Blood Cancer Institute’s (CBCI) Sarah Cannon Research Institute (SCRI), US, ...

The bone-marrow picture can present in one of several ways: The marrow is diagnostic of acute leukemia, with a marked infiltration of blast cells (as in Case 1). The marrow is normocellular or ...

5D). These results indicate that NADPH-dependent oxidative burst activity is carried out by fractions enriched in macrophage-like (ML) cells and blast-like cells (ABL and BBL). Previous studies have ...

With AML, Olivia explained: “Even if there’s a speck of it left, it just regrows. “And what regrows is basically the resistant cells, the ones that have evaded and resisted the previous ...

BPDCN is an aggressive type of blood cancer that originates from plasmacytoid dendritic cells (pDCs), a component of the immune system that produces type 1 interferon cytokines. These cytokines ...

There are no standardized guidelines on what to use. We often borrow regimens from acute myeloid leukemia [AML], extrapolate them to blast-phase CML, and add TKIs. But there’s no clear guideline or ...

The researchers began by finding DNA aptamers that seek out markers found on the surface of acute myeloid leukemia stem cells. They wanted to target not just the cancer, but the stem cells ...

it has been observed that both Faecalibacterium and Roseburia were significantly reduced in the gut microbiota of AML patients. These reductions are negatively correlated with peripheral leukocyte ...

Studies have shown that differentiated monocyte-like AML cells can express various immunomodulatory factors ... Furthermore, we analyzed the relationship between AML susceptibility, bone marrow (BM) ...