Key Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China ...
Our STEAP1 CAR T cells demonstrated potent anti-tumor efficacy and prolonged persistence in preclinical mCRPC models, including human-in-mouse (C4-2B, 22Rv1) and mouse-in-mouse (RM9) systems. Safety ...
High-throughput transcriptome analysis revealed that ferroptosis-related genes are significantly regulated in androgen receptor-dependent cells 22Rv1 and LNCaP, and less significantly in androgen ...
In patients with castration-resistant prostate cancer (CRPC), clinical resistances such as androgen receptor (AR) mutation, AR overexpression, and AR splice variants (ARVs) limit the effectiveness of ...
2020b; Xie et al., 2020). Human PCa cell lines (22RV1 and DU145) and kidney cell line (293T) were purchased from ATCC. 22RV1 and DU145 cells were cultured in 1640 and Dulbecco modified Eagle medium ...
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