Check out same-game parlay possibilities for when NFC West foes meet as the San Francisco 49ers (5-4) and the Seattle ...

San Francisco head coach Kyle Shanahan discussed Friday the 49ers' offensive line ahead of a matchup with the Seattle ...

The NFL has fined two San Francisco 49ers players from last Sunday's win in Tampa against the Buccaneers. FB Kyle Juszczyk ...

The San Francisco 49ers boast one of the deepest WR groups in the league, but they could be ditching one of their best ...

Local sports talk radio station KNBR is moving its studios out of San Francisco and plans to operate out of Santa Clara at ...

The 49ers are back in action on Sunday against the visiting Seahawks, and have made several notable roster moves.

Deommodore Lenoir and the San Francisco 49ers agreed to a contract extension on Wednesday. This marks the first time the 49ers extended a cornerback that they d ...

San Francisco 49ers cornerback Deommodore Lenoir discussed his decision to stay in The Bay through the 2029 season and the ...

San Francisco 49ers defensive lineman Sam Okuayinonu joined the 49ers "You've Got Mail" podcast presented by Delta Dental to ...

The Seattle Seahawks will visit the San Francisco 49ers in a key game in the NFC West race with both teams trying to catch ...

SANTA CLARA, Calif. — The season debut of Christian McCaffrey helped make the San Francisco 49ers’ offence look more like it did a year ago than it did in an up-and-down first half of the season.

The Seattle Seahawks will take on the San Francisco 49ers on Sunday. It will be the rematch of Week 6, when San Francisco ...