C&EN28d
Tetrahedral-DNA-Nanostructure-Modified Engineered Extracellular Vesicles Enhance Oral Squamous Cell Carcinomas Therapy by Targeting GPX4
Department of Head and Neck Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center University of Electronic Science and Technology of China, ...
SciELO6d
circLOC375190 promotes autophagy through modulation of the mTORC1/TFEB axis in acute ischemic stroke-induced neurological injury
circLOC375190 affects AIS autophagy by regulating the mTORC1/TFEB axis. Therefore, to provide a theoretical foundation for the treatment of AIS, the authors explored the specific mechanism of ...
Frontiers20d
Paeonol ameliorates ferroptosis and inflammation in chondrocytes through AMPK/Nrf2/GPX4 pathway
Western blotting and immunofluorescence staining were used to detect biomarker proteins of ferroptosis, inflammation, and AMPK/Nrf2/GPX4 signaling pathway proteins. Results: The results showed that ...
Frontiers27d
Crosstalk between ferroptosis and innate immune in diabetic kidney disease: mechanisms and therapeutic implications
GPx4, Glutathione Peroxidase 4; GSSG, oxidized glutathione; GSR, glutathione reductase; SLC7A11, Solute Carrier Family 7 Member 11; Nrf2, Nuclear factor erythroid 2-related factor 2; ATF4, activating ...