This study provides compelling evidence that kinesin's stepping mechanism is governed by strain-induced conformational changes in its nucleotide-binding pockets. Using pre-steady state kinetics and ...

Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...

Methods We overexpressed GFP tagged wild-type (WT) and I73T SFTPC in HeLa cells ... Conclusion We have shown that pathogenic SFTPC mutant I73T mistrafficks not only to the cell surface, but also into ...

This study shows that RNA decay rather than the presence of premature termination codons triggers a TA-like response.

Untold mutant stories like Magneto and Professor X's origins provide opportunities for intense, gritty missions. X-Men '97 has been Marvel’s biggest nostalgia-packed comeback, and fans are ...

Instead of dreaming up new tales of radioactive spiders and gamma bomb explosions, Lee could just say that new characters were born as mutants, and that was enough. Whatever Lee intended when he ...

The discovery of the new mutant strain came as the World Health Organization extended its declaration of a public health emergency of international concern (PHEIC) over the mpox epidemic.

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Biomedical applications of hydrogels are rapidly increasing due to their special ...