A CHARITY event in Garelochhead later this month will raise money for a toddler with a rare disease. Project 81 Youth and Community Enterprise is organising a fundraising event on Saturday, March 29, ...
This includes X-linked lymphoproliferative-1 (XLP-1) SH2D1A mutation affecting SLAM-associated protein (SAP) and XLP-2 BIRC4 mutation affecting X-linked inhibitor of apoptosis (XIAP) protein. IL-18 ...
A related strategy is the inhibition of X-linked Inhibitor of Apoptosis Proteins (XIAP), a family of proteins which block apoptosis by directly binding and inhibiting caspases, and which are ...
3). Furthermore, the GPHN.FingR-XIAP (GFE3), a protein very similar to the complex formed following activation of paGFE3 and chGFE3, has been extensively tested by us and others in vivo(1-4). For ...
Our immunology evaluation did not reveal any evidence of immune deficiency, however XIAP deficiency and other primary immune deficiencies remain unlikely, given the clinical presentation, and there ...
This valuable study on Pseudomonas subverting host immunity identifies a new immune evasion strategy. There is solid evidence for the cleavage of VgrG2B by Caspase 11 and the generation of fragments ...
Future Microbiol. 2012;7(6):719-731.
Mitochondria are versatile organelles and essential components of numerous biological processes such as energy metabolism, signal transduction, and cell fate determination. In recent years, their ...
2 Department of Rheumatology and Clinical Immunology, Semmelweis University, Budapest, Hungary 4 Department of Genetics, Cell and Immunobiology, Semmelweis University, Budapest, Hungary 5 Heart and ...
The acquired assets will support and diversify Genzyme's gene therapy research program. with the Breaking Science News daily newsletter ...
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