The cause of the original case or cases of BSE is currently unknown. Sheep scrapie or a previously undetected bovine transmissible spongiform encephalopathy (TSE) that arose spontaneously have ...

More ominously, the sheep might even be harboring the most dreaded strain of TSE: bovine spongiform encephalopathy, BSE, the so-called mad cow disease. The owners recoiled. These were prize flocks ...

Viruses, not prions, may be at the root of diseases such as scrapie, BSE and variant Creutzfeldt ... that tiny virus-like particles observed in TSE-infected brains may be the culprits.

For many years, scrapie from different sheep breeds and TSE diseases from other animals, e.g. scrapie from goats and BSE from cattle, have been used to infect laboratory mice. In these mice the ...

of the Canadian BSE Reference Lab, Canadian Food Inspection Agency, Lethbridge Laboratory, Lethbridge, Alberta (Canada). “The result is that many countries have enacted TSE surveillance programs ...

All commonly used processes in the bovine bone gelatin manufacturing process that have the potential to remove and/or inactivate BSE pathogens, are totally effective, according to the results of a ...

BSE infectivity in sheep quantitatively, by stage of incubation, tissue and sheep genotype; (4) age-dependent susceptibility to TSE infection in a variety of species, including sheep and cattle ...

Then BSE-infected meat turned up in butcher shops ... The disease was dubbed Transmissible Spongiform Encephalopathy. Sporadic TSE results from spontaneous mutation of the prion.

The BSE and scrapie leaflets were last issued in 2000 and 1999 respectively and have been updated to reflect a number of key developments. These include: The implementation of the TSE Regulations ...

A European Food Safety Authority (EFSA) working group on TSE testing has approved one new rapid BSE test and two for TSEs in sheep and goats. A European Food Safety Authority (EFSA) working group ...

on research into TSE’s affect on animals and humans. Said the inventory: “This is a large programme, which has developed progressively since the beginning of the BSE epidemic in cattle.