Yahoo Finance22d
Hoth Therapeutics Announces Positive Findings on GDNF's Potential as a Game-Changer in Obesity Treatment and Reduced Fatty Liver Disease
Inhibition of Fat Cell Formation (Adipogenesis) – GDNF suppressed key genes involved in fat storage, including PPAR-γ, FASN, and SREBF1, while promoting fat oxidation pathways. Improved Insulin ...
SciELO9d
Probing of MEP1A gene to identify biomarkers associated with post-partum anestrus in buffalo
Post parturition period during which female animal does not exhibit estrus behavior and is unable to get successfully fertilized and conceive is known as post-partum anestrus. It causes buffalo ...
Frontiers27d
Research progress on ferroptosis in Myelodysplastic syndromes
A set of six feature genes (SREBF1, PTPN6, PARP9, MAP3K11, MDM4, EZH2) demonstrated high accuracy in MDS diagnosis. These findings underscore the complex relationship between FRGs and MDS (Zhu et al., ...
Frontiers10d
Role of genetic variants and DNA methylation of lipid metabolism-related genes in metabolic dysfunction-associated steatotic liver disease
1 Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Department of Basic Medicine, Gannan Medical University, Ganzhou, China 2 Department ...
gut.bmj22d
Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans
Objective Increased de novo fatty acid (FA) synthesis and cholesterol biosynthesis have been independently described in many tumour types, including hepatocellular carcinoma (HCC). Conclusion Our ...