Oxysterols are a class of molecules derived from cholesterol via oxidation or as byproducts of cholesterol synthesis. Despite ...

This impairs the structural integrity and bending properties of the plasma membrane, compromising the ability of the Schwann cells to 'wrap' around the peripheral nerves, producing a lipid-rich ...

Familial dysautonomia (FD) is a rare but fatal disorder primarily affecting the peripheral nervous system. We have demonstrated ... Other iPSC-based models affecting neural crest lineages include ...

The company has several preclinical programs for neurodegenerative disorders of the eye, central nervous system ... of peripheral myelin protein 22 (PMP22), and impacts Schwann cell survival ...