A recent study has uncovered the pivotal role of the transcription factor SOX9 in the development of hypospadias, a common congenital condition that affects male children.

Dr. Xing Liu, the lead researcher, stressed the significance of the findings: "This is the first study to pinpoint SOX9 as a key player in hypospadias development. By understanding how SOX9 ...

Polycystic kidney disease (PKD), a family of genetic disorders that causes clusters of cysts to form on the kidney, is among the most common genetic disorders, affecting some 500,000 people in the ...

EMBL Barcelona researchers developed a new computational method to reconstruct embryonic development Laura Aviñó-Esteban from ...

Endochondral ossification is hard to recapitulate with human cells. Here, the authors generated SOX9+ sclerotomal progenitors from hPSCs, modeling key developmental stages of bone development and ...

A recent study has uncovered the pivotal role of the transcription factor SOX9 in the development of hypospadias, a common congenital condition that affects male children. The research highlights how ...

uclouvain.be. Objective The transcription factor SOX9 was recently shown to stimulate ductal gene expression in pancreatic acinar-to-ductal metaplasia and to accelerate development of premalignant ...

Further study of the mice with the Fbxw7 gene deletion revealed that renal function declines were connected to an abnormal accumulation of a protein called SOX9. Normalizing its levels by genetically ...

Evolution and Recent Radiation Therapy Advancement in Uganda: A Precedent on How to Increase Access to Quality Radiotherapy Services in Low- and Middle-Income Countries Variations in somatic genetic ...

Greek philosopher Empedocles thought that different temperatures produced different sexes—while others were decidedly ...