the authors show how STAMBPL1 promotes TNBC angiogenesis via a feed-forward GRHL3/HIF1a/VEGFA axis. They demonstrate that STAMBPL1 interacts with FOXO1, define the required domains in each protein, ...
© 2025 American Heart Association, Inc. Departments of Surgery (T.M.B., J.M., J.S., S.B., K.A.G.), University of Michigan, Ann Arbor. Departments of Surgery (T.M.B ...
The Buddhasothorn Asthma Severity Score (BASS): A practical screening tool for predicting severe asthma exacerbations for pediatric patients.
In this study, we discovered that STAMBPL1 facilitates the transcriptional regulation of GRHL3 by interacting with FOXO1, consequently enhancing HIF1A transcription through GRHL3 to activate the HIF1α ...
Metabolic adaption is crucial for the heart to sustain its contractile activity under various physiological and pathological conditions. At the molecular level, the changes in energy demand impinge on ...
In cultured hepatocytes and mouse livers, alcohol exposure inhibited forkhead box protein O1 (FoxO1) expression, which correlated with miR-148a levels and significantly decreased in human AH specimens ...
World population has been continuously increasing and progressively aging. Aging is characterized by a complex and intraindividual process associated with nine major cellular and molecular hallmarks, ...
Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration.
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