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Background: Stroke is the second leading cause of death and the third leading cause of disability worldwide, with ischemic stroke (IS) being the most prevalent. A substantial number of irreversible ...

The nuclear factor of activated T cells (NFAT5), also known as a tonicity-responsive enhancer-binding protein, was originally identified as a key transcription factor involved in maintaining cellular ...

Despite the wealth of available information regarding the activation by Akt, there remains a paucity of information regarding the cellular mechanisms that lead to Akt inactivation. In general, the ...