SciELO6d
circLOC375190 promotes autophagy through modulation of the mTORC1/TFEB axis in acute ischemic stroke-induced neurological injury
circLOC375190 affects AIS autophagy by regulating the mTORC1/TFEB axis. Therefore, to provide a theoretical foundation for the treatment of AIS, the authors explored the specific mechanism of ...
Frontiers1d
MEPED as salvage therapy for relapsed/refractory Hodgkin’s lymphoma incorporating edited non-oncogene addiction: mTOR as a bottleneck
MEPED edits everolimus activities in such a way that mTORC1 becomes a non-oncogene addiction bottleneck, hence determining long-term therapy outcome. The implications of the therapeutic paradigm shift ...