Innovations in therapeutic strategies, coupled with a deeper understanding of breast cancer biology, will be essential for advancing personalized ...

A new review was published in , Volume 16, on March 13, 2025, titled "Signaling pathway dysregulation in breast cancer." ...

Verastem (NASDAQ:VSTM – Free Report) had its price objective cut by Royal Bank of Canada from $16.00 to $14.00 in a report released on Friday morning,Benzinga reports. They currently have an ...

The deal marks growing interest in SHP2 as a target among cancer drug developers, inspired by the promise of targeting cancer-associated molecular pathways upstream of other targets like RAS/ERK ...

A breakthrough in lung cancer treatment may be on the horizon. Scientists at VCU Massey Comprehensive Cancer Center have uncovered a powerful ...

Aberrant activation of the Ras/Raf/MAPK/ERK kinase/extracellular signal-regulated kinase cascade and the VEGF pathway are commonly observed in breast cancer cells leading to malignant cell ...

FGTI-2734 blocks cancer cells' wild type RAS membrane localization, prohibiting a cellular process called ERK reactivation, ...

The MAP kinase pathway involving Raf, MEK, and ERK, initiated by Ras, leads to Halloween gene expression responsible for Ecdysone synthesis and release. Ecdysone is converted to active ...