Verastem Oncology , a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, announced today multiple oral and poster presentations at the ...

1 Division of Infectious Diseases, Department of Pediatrics, Washington School of Medicine in St. Louis, St. Louis, MO, United States 2 Division of Immunobiology, Department of Pathology and ...

More than half of patients with ischemic stroke experience futile reperfusion, increasing the risk of death and disabilities despite a successful recanalization. The reason behind this is debated, and ...

Janus kinase/signal transduction and transcription activation (JAK/STAT) pathways were originally thought to be intracellular signaling pathways that mediate cytokine signals in mammals. Existing ...

Correspondence to Dr David G DeNardo, Medicine, Washington University, St. Louis, MO 63132, USA; ddenardo{at}wustl.edu Results In KPC mice, the expression levels of phosphorylated STAT3 (pSTAT3) were ...