Hum Mol Genet 2019;28:2486-2500 Chang W, Wang Y, Luxton GWG, Ostlund C, Worman HJ, Gundersen GG. Imbalanced nucleocytskeletal connections create common polarity defects in progeria and physiological ...

As an example, base editing in animal models has been shown to be able to modify the mutant gene that causes progeria and reduce the disease’s effects. In the context of genetic diseases, genome ...