The evidence supporting the claims of the authors is solid, although the inclusion of additional data showing the mechanisms by which PLP1+ enteric glia acts on Paneth cells would have strengthened ..

Alterations in virtually all intestinal cell types, including immune, epithelial and stromal cells, have been described in these diseases. The study of IBD has historically relied on bulk ...

Results The p53 mutation acts as a switch to expand progenitor cells and inhibit their differentiation towards metaplasia, but only amidst chronic injury. In L2-IL1β mice, p53 mutation increased ...

In 2009, Jonathan Weissman was hunting for a new way to spy on what happens inside a cell. In particular, the molecular cell biologist wanted to know what proteins are produced at any given moment.

Nancy Leftenant-Colon, who battled racial discrimination in a barrier-breaking career as a military nurse, serving as the first African American in the regular Army Nurse Corps and later caring ...

She was later an Air Force officer. By Clay Risen Nancy Leftenant-Colon, a granddaughter of enslaved people who in 1948 became the first Black nurse to serve in the regular U.S. armed forces ...

She was 104. Nancy Leftenant-Colon, who retired as a major and died earlier this month at a New York nursing home, was remembered by relatives and friends for quietly breaking down racial barriers ...

Moreover, the expression of specific markers of lymphangiogenesis, such as transcription factor Prox-1, growth factor VEGFR3, or protein FOXC2, were significantly decreased in Paneth cell depleted ...

Intestine is composed of various types of cells including absorptive epithelial cells, goblet cells, endocrine cells, Paneth cells, immunological cells, and so on, which play digestion, absorption, ...

Although metaplastic Paneth cells are part of the overarching pathology of intestinal metaplasia (IM), only a fraction of intestinal metaplastic lesions contain Paneth cells. We survey literature ...