According to the World Health Organization (WHO), over 22% of the global population smokes, with more than 9 million smoking-related deaths reported annually. Effective treatments to alleviate ...

biomarker identification to link nicotine abuse liability with the upregulation of nicotinic acetylcholine receptors (nAChRs), a critical indicator of addiction; and neurophysiological evaluation ...

Weng and his team reveal that out of hundreds of animal species, amphibians, specifically frogs, have the highest number of bitter taste receptors, known as TAS2Rs. While humans have 25 TAS2Rs ...

Pain is an example of an important sensory neuron. When you feel pain from a hot pan or a sharp pin, you are sending sensory information via sensory neurons up to the brain. The flow of electrical ...

NMDA receptors, members of the excitatory ionotropic glutamate receptor family, are essential to these processes. They regulate the strength of synaptic connections, playing a critical role in ...

Nicotine molecules bind to the body’s nicotinic acetylcholine receptors, which are involved in regulating the dopamine reward system, and the resulting feel-good sensation is what makes nicotine ...

While previous research has highlighted the key role of the cNTS in food intake regulation, the unique contribution of the different neuron subtypes within this brainstem region and the mechanisms ...

Nicotinic receptors are also present on the postsynaptic junctional folds, opposite the sites on the nerve endings from which acetylcholine is released. These nicotinic receptors are composed of ...

Study of 2.4 million participants reveals potential advantages for cardiometabolic and psychiatric conditions alongside increased risks of gastrointestinal and musculoskeletal issues Study ...

Department of Pharmaceutical Sciences, Medicinal Chemistry Section “Pietro Pratesi”, University of Milan, Via L. Mangiagalli 25, Milan 20133, Italy ...