Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen 2100, Denmark ...

autosomal dominant families with mutations of the neuronal nicotinic acetylcholine receptor gene on chromosomes 20q and 15 respectively have been reported. Ekbom's syndrome has become de rigeur as a ...

We investigated the neural pathway involved and the cells mediating ... To define the possible role of α7 nicotinic acetylcholine receptor (α7nAChR), we used knockout and bone marrow chimaera mice.

AME can significantly increase Aβ uptake by mouse N2a neural cells through class A scavenger ... Molecular docking experiments were conducted with the human α7 nicotinic acetylcholine receptor ...

Striatal dopamine (DA) release regulates reward-related learning and behavioural activation and is believed to consist of a short-lived phasic and continuous tonic component. Here, we build a ...

biomarker identification to link nicotine abuse liability with the upregulation of nicotinic acetylcholine receptors (nAChRs), a critical indicator of addiction; and neurophysiological evaluation ...

Nicotine molecules bind to the body’s nicotinic acetylcholine receptors, which are involved in regulating the dopamine reward system, and the resulting feel-good sensation is what makes nicotine ...

Dr. Heh-In Im at the Center for Brain Disorders of the Korea Institute of Science and Technology (KIST) has identified a novel brain region and neural mechanism involved in regulating nicotine ...

Studies reported that salsolinol may exert some of the effects of ethanol by activating μ opioid receptors on GABAergic neurons signaling ... 2019), increased neuronal excitability, and enhanced ...

Feb. 19, 2025 — Researchers find large language models process diverse types of data, like different languages, audio inputs, images, etc., similarly to how humans ...