Following up on Miwa’s work, lead author of the Neuron paper, Inés Ibañez-Tallon, used antibodies specific to lynx1 to reveal in mice that the protein was closely associated with the nicotinic ...

In particular, the finding that acetylcholine-receptor antagonists have an antiproliferative effect on neural stem cells has important implications for the understanding and treatment of Alzheimer ...

To facilitate the transport of siRNA across the BBB, the authors took advantage of a strategy that enables the rabies virus to enter neuronal ... to the nicotinic acetylcholine receptor (AchR ...

Nicotinic receptors are also present on the postsynaptic junctional folds, opposite the sites on the nerve endings from which acetylcholine is released. These nicotinic receptors are composed of ...

the researchers traced the problem to reduced activation of nicotinic receptors by acetylcholine, another neurotransmitter important for decision-making. The study helps to explain the ...