Although the cause of multiple myeloma is not known, research shows that genetic changes in the DNA of a single plasma cell ...

Study reveals multiple high-risk genetic changes predict worse multiple myeloma outcomes across all treatments.

In spite of recent advances in the management of multiple myeloma, cure has been elusive, with efforts to improve long-term ...

Computed tomography (CT) is a sensitive tool for detection of the bone-destructive effects in MM as it can detect small osteolytic lesions ... is a hallmark of multiple myeloma (MM), associated ...

It develops when a normal plasma cell changes into a myeloma cell, which can multiply uncontrollably. Multiple myeloma symptoms include bone pain or fractures, backache, frequent infections, weight ...

Multiple myeloma, an incurable type of bone marrow cancer, often develops unnoticed in the bone marrow over decades. In advanced stages, lesions form that can destroy the bone and spread to other ...

Background. Unicameral bone cyst (UBC) is the most common benign lytic bone lesion seen in children. The aim of this study is to investigate clinical factors affecting pathological fracture and ...

hsr.it Objective To characterise in vivo the microstructural abnormalities of multiple sclerosis (MS) normal-appearing (NA) cortex and cortical lesions (CLs) and their relations with clinical ...

me.com Objectives To determine the frequency of hypothalamic lesions in patients with multiple sclerosis (MS) using conventional MRI (cMRI) protocols. Methods Brain cMRI (1.5 Tesla) scans of 105 ...

The team tackled a critical challenge in treating multiple myeloma—a blood cancer where malignant plasma cells accumulate in bone marrow, leading to debilitating bone lesions in 80% of patients.

Some people with multiple myeloma have no signs or symptoms at all. But sometimes multiple myeloma does cause symptoms, including bone pain or weakness, infections, low blood counts, or other problems ...