In the second half of the 20th century, ADCs rapidly progressed from rudimentary constructs of polyclonal antibodies noncovalently linked to a cytotoxin, to mouse monoclonal antibodies (mAbs), and ...

In contrast to polyclonal antibodies, monoclonals are highly specific ... 2 Since 1986, over 117 monoclonal antibodies have been FDA-approved, beginning with the mouse monoclonal antibody ...

The human anti-mouse antibody (HAMA) reaction limits the therapeutic utility of mouse monoclonal antibodies. Humanization of mouse monoclonal antibodies by genetic engineering can improve the in ...

Pleasanton, California - Boster Bio Technology unlocks insights into cancer and neurological disorders with high-quality ...

A second mouse line (Ntv-a ... K-Ras expression was detected by a polyclonal antibody to K-Ras (Santa Cruz) after treatment of the sections with antigen retrieval solution (Dako) according ...