Methotrexate (MTX) is the widely agreed upon first-choice second-line agent to treat juvenile idiopathic arthritis (JIA), up to 75% of JIA patients in recent registries have used MTX at some time ...

Purpose: The pharmacology, pharmacokinetics, clinical efficacy, safety, and role of tocilizumab in rheumatoid arthritis (RA ... both as a combination with methotrexate and as monotherapy, has ...

Objective: To compare the clinical efficacy of methotrexate and tolerance to the drug in patients with rheumatoid arthritis who were switched from intramuscular to oral administration because of a ...

hss.edu Objective To determine the comparative effectiveness of oral versus subcutaneous methotrexate (MTX) as initial therapy for patients with early rheumatoid arthritis (ERA). Methods Patients with ...

Using glucocorticoids, rituzimab, or certain immunosuppressants to treat connective tissue diseases is associated with ...

Children with rheumatic diseases may face increased risks for COVID-19-related hospitalization, particularly those using glucocorticoids, rituximab, or mycophenolate.

Rheumatoid arthritis (RA) is an autoimmune disorder characterized ... The DMARDs are divided into conventional synthetic (cs) DMARDs (such as methotrexate, leflunomide and sulfasalazine), biological ...

Are you struggling with joint pain or stiffness? Arthritis can make even the simplest daily tasks, like walking or opening jars, feel like a challenge. It is a condition that brings constant ...

Rheumatoid arthritis (RA) is an inflammatory, autoimmune condition that affects not only joints but also organs, including eyes. While it can have painful and debilitating effects if left untreated, ...

The odds of developing systemic lupus erythematosus or systemic sclerosis appear to significantly increase with the use of menopausal hormone therapy, according to data published in Rheumatology.