Methotrexate (MTX) is the widely agreed upon first-choice second-line agent to treat juvenile idiopathic arthritis (JIA), up to 75% of JIA patients in recent registries have used MTX at some time ...

Synovial biopsy has revealed suggestive features for juvenile idiopathic arthritis (JIA ... anti-inflammatory drugs and methotrexate. Even under methotrexate therapy, the joint function has ...

The study’s small size limits interpretation, but it remains the largest real-world data available, experts said.

Family History A child's chance of developing juvenile autoimmune arthritis (JIA ... are frequently used to treat pain and ...

Methotrexate sodium 2.5mg; scored tabs. Be fully familiar with this drug's toxicity before use. Obtain baseline and monitor CBCs for myelosuppression, and hepatic, renal and pulmonary function ...

Juvenile idiopathic arthritis is the most common rheumatic disease in children. Glucocorticoids (oral and intravenous) and methotrexate are the standard of care, even with limited evidence about ...