Nevertheless, such mechanisms appear to play a significant role in the acquisition of resistance to cancer drugs, and while they remain poorly characterized thus far, evidence highlighting their ...

Drug resistance is one of the greatest challenges in cancer treatment. Therefore, understanding its mechanisms is essential for developing new therapies. The study also identified methods to ...

A new case report details a novel genetic mutation linked to drug resistance in a non-small cell lung cancer patient ...

Understanding the mechanisms of resistance to cancer treatments is necessary to find effective therapies at different stages of the disease. Scientists at UT Southwestern Medical Center studied the ...

Danés, principal investigator of the Cancer and Stem Cell Biology Lab at the Champalimaud Foundation, in Lisbon, has shown ...

A joint research team from the LKS Faculty of Medicine (HKUMed) and the Faculty of Science at the University of Hong Kong has uncovered an unexpected interaction between chemotherapeutic agents and a ...

Cancer cells have special adaptation mechanisms that allow them to proliferate despite changes in their genetic makeup.

This mechanism not only allows cancer cells ... Photosensitizer to Overcome Drug‐Resistant Cancer via Oxidative Autophagy Inhibition, Advanced Science (2024). DOI: 10.1002/advs.

A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled "Acquired RUFY1-RET rearrangement as a mechanism of resistance to lorlatinib in a patient with CD74-ROS1 ...

The relatively new paradigm of 'rationally targeted' cancer drug therapies ... commonly used chemotherapy drugs, establishing specific molecular mechanisms of resistance has been very challenging ...

A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled “Acquired RUFY1-RET rearrangement as a ...