In a new study published in Nature, led by scientists at the Allen Institute, La Jolla Institute for Immunology, and UC San Diego, researchers reveal how cells known as tissue-resident memory CD8 ...

With the aging process, the risk of developing cancer ... of the E3 ubiquitin ligase BFAR inhibited the production of TRM cells among CD8 + T cells derived from elderly individuals.

BrightPath Bio and Cellistic have entered a process development and manufacturing agreement ... tumour activity through the priming of host CD8+ T cells—a mechanism expected to evade host ...

Although effector activity and memory formation in CD8 + T cells are known to depend on ... yet the regulatory mechanisms of this process are not fully defined. Here, the authors identify ...