Mdm2.RING ubiquitinates PSD-95 ... After photocleavage with 400 nm light, PBP binds photocleaved PhoCl, recruiting the E3 ligase domain, which ubiquitinates Gephyrin and targets it for degradation by ...

For paGFE3 and chGFE3, the E3 ligase (RING domain of Mdm2) is overexpressed and thus freely diffusible within the cell as a separate construct. Although the authors show that Gephyrin is not ...

(93) experimentally investigated fluorescently labelled p53 and Mdm2 dynamics in living breast cancer (MCF7 ... fractal dynamics and algorithmic complexity measures, in this domain of research.

Genetic engineering techniques were applied to investigate the regulatory relationships among phosphatidylinositol 3-kinase (PI3K), protein kinase-B (AKT), murine double minute-2 (MDM2), protein 53 ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Oscillatory p53 expression occurs in ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Aberrant mitochondrial function has been ...

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