The function of lysosomes is tightly regulated by complex cellular signals, including calcium ions moving into and out of lysosomes. Scientists have known how lysosomes release their calcium since ...

The humble lysosome, which carries out so many essential functions, appears to live a double life as a potential traitorous agent. "The study highlights the close interaction between lysosomal ...

2024). The primacy of endolysosomal dysfunction in neurons and microglia aligns with a recent report that, in AD, both ApoE and Aβ aggregate within the microglial lysosome, compromising its function ...

Strengths: The implications for health, disease, and therapeutic discovery are considerable, given the central role of autophagy and lysosome-related pathways in regulating critical cellular processes ...

Understanding how MLRO functions could lead to new therapeutic ... More information: Xiaowen Ma et al, Perspectives of mitochondria-lysosome-related organelle in hepatocyte dedifferentiation ...

Visualizing cells after editing specific genes can help scientists learn new details about the function of those genes. But ...

GENFI Top Hits. CSF proteomics linked abundance of CALB2, GRN/NAGA, and PEA15/SEMA6A to C9ORF72 (gold), GRN (red), and MAPT ...

Researchers identify target to enhance NK cell function for liver cancer therapy in Korea New insights into immune cell dynamics could lead to innovative therapies for cancer in Korea.

Gain Therapeutics (GANX) provided a letter to shareholders from the Company’s President and CEO, Gene Mack, which read in part,”With 2025 ...