Explore the critical differences in how women's pain is processed and how tailored treatments can alleviate chronic pain.

A new study shows that leptin sensitivity can be restored in mice, leading to weight loss. Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into ...

But now Bowen Tan, Kristina Hedbacker, and other researchers in Friedman's Laboratory of Molecular Genetics have discovered a neural mechanism involved in leptin resistance-and, crucially, a way to ...

The team found that rapamycin restores leptin sensitivity to diet-induced obese (DIO) mice, leading to significant loss of fat with only minimal effects on muscle. “Before our research ...

As the researchers describe in a paper in Cell Metabolism, the drug rapamycin restores leptin sensitivity to diet-induced obese mice, leading to significant loss of fat with only minimal effects ...

As the researchers describe in a new paper in Cell Metabolism, the drug rapamycin restores leptin sensitivity to diet-induced obese mice, leading to significant loss of fat with only minimal ...

Friedman’s laboratory at the Rockefeller University cloned the leptin gene in 1994. “Before our research, the cause of obesity in diet-induced obese mice was unknown, leaving a critical gap in our ...

As the researchers describe in a new paper in Cell Metabolism, the drug rapamycin restores leptin sensitivity to diet-induced obese mice, leading to significant loss of fat with only minimal ...

Abstract and Introduction Research Design and Methods Results Discussion References Finally, accelerated diabetes occurred in leptin-treated female mice only when leptin administration was started ...

As the only child of a self-employed and largely self-taught Canadian radio-and-refrigeration repairman, I spent much of my childhood investigating how things worked by taking them apart.