AP2A1 could serve as a biomarker for aging and a target for therapies aimed at slowing down or even reversing the aging ...

There are a multitude of products for sale that promise the appearance of eternal youth by erasing wrinkles or firming up jaw ...

Researchers from Osaka University found that knockdown of the Adaptor Protein Complex 2, Alpha 1 Subunit (AP2A1) rejuvenates ...

BACKGROUND: Circular RNAs derived from both nuclear and mitochondrial genomes are identified in animal cells.

TNF receptor 1 (TNFR1) is expressed in most cell types, and can be activated by binding of either soluble TNF (solTNF) or transmembrane ... of TNFR1-mediated signaling while sparing TNFR2 ...

Cite this: TNF Signaling Inhibition in the CNS: Implications for Normal Brain Function and Neurodegenerative Disease - Medscape - Oct 17, 2008.

revealing how cells control inositol pyrophosphate levels to regulate nutrient signaling. This study identifies the conversion of lysine to Δ 1-piperideine-6-carboxylic acid (P6C) via pipecolate ...

Toxin-antitoxin systems make up a branch of the bacterial anti-phage immune system. Here, Johannesman et al demonstrate that some phages have co-opted an orphan antitoxin to counter a DNA ADP ...