The scientists' new data show that paxillin binds directly to the intracellular part of integrin. It clings to the receptor, so to speak. Analysis of the 3D structure reveals an important piece of ...

Bioinspired materials are synthetic materials whose structure, properties or function ... demonstrate that cells can spread and form mature integrin adhesions on fluid substrates by interacting ...

Explore the role of the extracellular matrix (ECM) in prostate cancer progression and discover natural therapies, including ...

Electron microscopy showed an altered lamellar structure with disorientation of elastin fibers ... smooth muscle myosin, smooth muscle 22 and integrin β1, as well as a significant increase in calponin ...

Aided by the brilliant X-rays produced by synchrotron radiation at the Argonne National Laboratory in Illinois, a group of scientists from Northwestern University have determined the complete ...

The company also develops RAD 302, an avß6-integrin targeting agent for the treatment of multiple cancer types; RAD 101 and RAD 102 for brain metastases; RAD 402 to treat advanced prostate cancer ...

The physiological and biochemical data that the authors present argues for an integrin activation that happens in 0.1 to 0.5 seconds, resulting in a sudden arrest. "For a long time, it was believed ...

Earth's inner core may actually have two distinct layers. (alexlmx/Canva Pro) "We found evidence that may indicate a change in the structure of iron, which suggests perhaps two separate cooling events ...

TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan, China Oncology Teaching and Research ...

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) constitutes a critical therapeutic approach for patients with malignant hematological disorders. Nevertheless, acute graft-versus-host ...

1 Department of Medicine, Division of Gastroenterology & Hepatology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK 2 Wellcome Trust PhD Programme for Clinicians, Cambridge Institute ...