AP2A1 could serve as a biomarker for aging and a target for therapies aimed at slowing down or even reversing the aging ...

Department of Nuclear Medicine, School of Medicine & Health, Klinikum rechts der Isar, TUM University Hospital, Technical University of Munich, Ismaninger Strasse 22, Munich 81675, Germany Central ...

On the other, high levels of αVβ3 integrin expression correlate with a more aggressive phenotype (figure 2). These findings have direct translational importance. As thyroid dysfunction is often ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from ...

Area under the curve of TSH after levothyroxine withdrawal versus administration of recombinant human TSH (rhTSH): possible implications for tumor growth ...

Not all stressors have the same impact on health. Stress arising from threats to social safety is most likely to affect psychological, biological, and clinical outcomes. This is the conclusion ...

was originally discovered as a plasma membrane molecule that copurified with the leukocyte and placental integrin αvβ3. Molecular cloning showed that the protein is identical to the cancer antigen ...

by upregulating integrin αVβ3 expression and activating downstream FAK/AKT and ERK signaling pathways that promote tumor cell proliferation (17). Integrin αVβ6. Integrin αVβ6 binds with OPN on the ...

We speculate that this pathway is turned on by the increased αvβ3 expression on the surface of endothelial cells. Activated endothelial cells also express adhesion molecules, such as P-selectin, which ...