On the other, high levels of αVβ3 integrin expression correlate with a more aggressive phenotype (figure 2). These findings have direct translational importance. As thyroid dysfunction is often ...

This is believed to be the result of the developmental lineage of melanocytes in the neural crest, allowing melanoma cells to undergo an EMT-like transition to facilitate metastasis by varying the ...

AP2A1 could serve as a biomarker for aging and a target for therapies aimed at slowing down or even reversing the aging ...

The key to reversing cellular aging may lie in a protein responsible for toggling cells between a "young" and an "old" state.

Researchers from Osaka University found that knockdown of the Adaptor Protein Complex 2, Alpha 1 Subunit (AP2A1) rejuvenates ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from ...

Gerry Baker is Editor at Large of The Wall Street Journal. His weekly column for the editorial page, “Free Expression,” appears in The Wall Street Journal each Tuesday. Mr. Baker is also host ...

Department of Nuclear Medicine, School of Medicine & Health, Klinikum rechts der Isar, TUM University Hospital, Technical University of Munich, Ismaninger Strasse 22, Munich 81675, Germany Central ...

Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia 22904, United States Carter Immunology Center and University of Virginia Cancer Center, University of Virginia ...

Cardiovascular and cardiometabolic diseases are leading causes of morbidity and mortality worldwide, driven in part by chronic inflammation. Emerging research suggests that the bone marrow ...