Here, the authors analyzed 2923 plasma proteins through prospective cohort and genetic analyses, identifying IL12B, CD6, MXRA8, CXCL9, IFNG, CCN3, RSPO3, and IL18 as prioritized potential ...

Results PPARg-agonist down-regulated PD1 mRNA/protein expression in mice and LAKs. In contact-dependent 3D co-cultures, PPARg-agonist in combination with IFNg promoted cell death of MSS+ tumor cells ...

Objectives This study aimed to identify plasma proteomic signatures that differentiate active and inactive giant cell arteritis (GCA) from non-disease controls. By comprehensively profiling the plasma ...

Background: Domestication of wild boars into local and intensive pig breeds has driven adaptive genomic changes, resulting in significant phenotypic differences in intestinal immune function. The ...

Pigs are a valuable human biomedical model and an important protein source supporting global food security. The transcriptomes of peripheral blood immune cells in pigs were defined at the bulk ...