PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...

Our cells harbor a DNA detector termed cGAS to inform the immune system of viral and bacterial infections, cell death, as ...

A research led by Sergio P. Acebrón, Researcher Ikerbasque at the UPV/EHU, develops a key tool to visualize the immune response to abnormal DNA, opening new avenues for the treatment of diseases.

Cells contain a DNA sensor called cGAS, which alerts the immune system to viral and bacterial infections, cell death, and cancer-related transformations. A research team led by Ikerbasque Research ...

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State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, China; Center for Translational Medicine, The First ...

Chemical Biology Program, Department of Pharmacology and Toxicology, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States ...