PT101 is an engineered IL-2 mutein fused to a protein backbone ... that are trying to flip that on its head and try to use the cytokine to protect organs from autoimmune reactions.

In fact, in pre-clinical and clinical studies, adenoviruses armed with cytokines such as GMCSF, TNFa and IL-2 conferred improved anti-tumor response, with enhanced effector CD8+ T and helper CD4+ T ...

Specific inflammatory cytokines can predict infection risk in leukemia in patients undergoing chemotherapy, according to a study in Microbial Pathogenesis.

After fixation and permeabilisation, these cells were stained with fluorochrome-conjugated antibodies against cytotoxic cytokines for 30 min at 4°C. The protocol was designed as a superiority trial to ...

Data reinforce dose-dependent mechanism with IMNN-001 100mg/m2 dose associated with 20% increase in IL-12 levels compared to 79mg/m2 doseResults ...

Coya Therapeutics' Phase 2 study shows monthly LD IL-2 improves cognitive scores and reduces inflammation in Alzheimer's patients, with no serious adverse events.

Compugen's innovative approach targets under-explored immune pathways like PVRIG and IL-18 binding protein. Read why I'm ...

Researchers from Rice University and Baylor College of Medicine have developed a new treatment that eliminates advanced-stage ...

Despite these limitations, the researchers believe the study confirmed the efficacy and safety of bimekizumab and brodalumab ...

New 2-year data show the long-term effects of bimekizumab on hidradenitis suppurativa, indicating its potential as a valuable ...