https://www.uksh.de/Das+UKSH/Presse/Presseinformationen/2025/Personalisierte+The... https://tu-dresden.de/med/mf/die-fakultaet/newsuebersicht/personalisierte-therap ...

Most patients were diagnosed with high-grade glioblastomas of the isocitrate dehydrogenase 1 gene (IDH1)/IDH2 wild type. A majority of the study participants previously received chemotherapy and ...

Mutations in RHOA, IDH2, and STAT3/5B influence peripheral T-cell lymphoma and large granular lymphocytic leukemia classification. Clonal T-cell receptor (TCR) gene rearrangement detection remains ...

with the total value of the deal potentially rising to $2 billion if Agios’ key pipeline candidate vorasidenib – a dual inhibitor of mutated IDH1 and IDH2 in trials for a form of brain cancer ...

The drug candidate – called vorasidenib – is a dual inhibitor of mutated IDH1 and IDH2, which is being developed for a hard-to-treat form of brain cancer called glioma. It was acquired by ...

Vorasidenib is an oral medication designed specifically to target low-grade gliomas that have mutations in the IDH1 or IDH2 genes. These mutations are found in the majority of low-grade gliomas and ...

Both these leukemias are caused by chance changes and mutations within the DNA. AML can be caused by changes within the FLT3, RAS, c-KIT, IDH1, IDH2, and various other genes. While these are mutations ...

New research by Yale has found an association between exposure to chemicals commonly used in firefighting and incidence of a ...

A young British woman who used to drink 12 cups of coffee a day and quit because of some caffeine withdrawal symptoms like ...