Humoral immunity refers to antibody-mediated immune responses. Antibodies are produced by plasma cells and protect the host from infection in three main ways: by binding to pathogens to inhibit ...

Our mechanistic understanding of humoral immune responses is mostly derived from vaccine studies that involve the injection of high antigen doses combined with adjuvants. These experimental models ...

Methods and analysis The primary outcomes for consideration are quality and quantity of immune responses (humoral and cell-mediated) post-pertussis vaccination. Of interest as secondary outcomes are ...

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...

Objectives Giant cell arteritis (GCA) and polymyalgia rheumatica ... of the SARS-CoV-2 vaccinations in patients with GCA/PMR, as determined by humoral and cellular immune responses. We also evaluated ...

Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its ...

In the current report, we could demonstrate that B cell depleting therapy with RTX affects the humoral immune response to SARS-CoV-2 vaccination in B cell depleted patients. However, humoral immune ...

Researchers at the Johns Hopkins Kimmel Cancer Center and Bloomberg-Kimmel Institute for Cancer Immunotherapy have developed ...

The more vigorous humoral immune response in females is also a consequence of the direct effects of oestrogens on B-cell function, which enhances neutralizing antibody production and thereby ...

When pathogens are not destroyed by the innate immune system, the adaptive immune response takes over. This is a highly specific response that involves specialised cells called lymphocytes and takes ...

In patients with RCC, exceptional response to immunotherapy may be related to clonal neoantigen-driven cytotoxic T-cell ...

Researchers at the Johns Hopkins Kimmel Cancer Center and Bloomberg~Kimmel Institute for Cancer Immunotherapy have developed a computer model to help scientists identify tumor-fighting immune cells in ...