Many drugs from different chemical classes and therapeutic areas have been shown to inhibit currents mediated via the hERG-coded ion channel, which is strongly correlated to a risk of inducing TdP.

While hERG channel is notoriously regarded as an off-target due to drug-induced cardiotoxicity, its therapeutic potential as a drug target remains largely unexplored. Methods: This study investigated ...

2010-2013: project associate - Regulation of overflow metabolism in filamentous fungi (FWF-project P22220); project completed (PhD-student: Anja Krüger) 2012-2015: project leader - Abiotic stress in ...

Department of Nanoscale Science and Engineering, College of Nanotechnology, Science and Engineering, University at Albany, Albany, NY, United States The evolution of stem cell-based heart models from ...

Standardized dried extracts listed according to their phytochemical marker employed for standardization and supplier. The analytical solutions of such dried extracts solutions were coded as: Hp, Gb, ...

Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea ...

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China University of Chinese Academy of Sciences, Beijing 100049, China ...