Methods: HBV‐persistent C57BL/6J mice were established through hydrodynamic tail vein injection of 10 µg pAAV‐HBV1.2 plasmid. Subsequently, mice treated i.p. with anti‐PD‐L1 and/or anti‐CTLA‐4 at ...

Its other HBV candidate is cavrotolimod, a spherical toll-like receptor 9 (TLR9) agonist designed to trigger innate and adaptive immune responses by binding to and activating the protein TLR9. The ...

We identify RIPK1 as the central component of the necrosome, forming the core of this complex. In addition, AlphaFold modeling provides insights into the structural mechanisms underlying RIPK1 ...

Most people can get the protein they need by eating a mix of animal and plant-based proteins in whole food. Protein supplements are better reserved for people who cannot consume enough protein through ...

And some seeds are impressively high in protein. "Seeds are a good source of plant-based protein, healthy unsaturated fat, fiber and other various micronutrients," says Natalie Rizzo, nutrition ...

PBGENE-HBV is designed to potentially cure chronic hepatitis B by eliminating the root cause of the virus. The Food and Drug Administration (FDA) has granted Fast Track designation to PBGENE-HBV ...