oral TLR7 agonist RG7854 and HBV core protein allosteric modulator RG7907. Dicerna is retaining an option to co-fund pivotal development of the product globally, which would entitle the company to ...

To address this, new antivirals targeting different components of the HBV molecular machinery are being developed. Here we investigated the hepatitis B core protein (HBc) that forms the viral capsids ...

In this paper, the authors present an interesting strategy to interfere with the HBV life cycle: the preparation of geranyl and peptides' dimers that could impede the correct assembly of hepatitis B ...

HBV-specific CD8 + T cells with different target specificities (HBV core epitope vs HBV polymerase (pol ... Checkpoint inhibition (in vitro blockade with anti-programmed cell death protein 1 ...

Future Virology. 2008;3(3):253-264. HBV budding is driven by the intrinsic property of the S-protein to form particles at the cytoplasmic side of the ER, even in the absence of mature nucleocapsids.

a satellite virusoid employing HBV envelope proteins for the entry into hepatocytes. To date, no effective therapy for HDV infection exists. Thus, entry inhibition may represent the first ...

Protein is kind of the It Girl of nutrients right now. It's the macro that's good at everything: building muscle, supporting immune function, sustaining energy levels, shoring up bone health, and ...

In a new study published in Nature, University of Missouri researchers have, for the first time, revealed the specific shape ...

Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional role in suppressing production of certain messenger RNAs and appear to help cells respond to ...

Getting enough protein daily is essential for your overall health. Healthy protein sources include eggs, nuts, lean meats, fish, dairy, and certain grains. Proteins are a large category of ...

Don’t overlook fruit when trying to add more protein to your diet. Fruit may not make the list of high-protein foods, but some options can provide the essential macronutrient, with the added ...