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Amyotrophic lateral sclerosis (ALS)—known as Lou Gehrig's Disease, based on the iconic 1930s New York Yankee baseball ...
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The authors demonstrate that Bcl11b is required within SCPNs for axonal outgrowth and proper entry into the internal capsule, while its expression in medium spiny neurons (MSNs) influences SCPN axon ...
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This important study identifies a mechanism by which caspases are activated in a non-lethal context to induce functional modulation in Drosophila olfactory receptor neurons. To deliver, the authors ...
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“As motor neurons degenerate and die, they stop sending messages to the muscles, which causes the muscles to weaken, start to twitch (fasciculations), and waste away (atrophy).” The brain ...